This book provides an analysis of the development and incidence of TIP in the Republic and its subcontinent, mainly but not entirely because of events between the collapse of apartheid and the present situation at the beginning of the third quarter of the 21^st century. This involves (a) defining the nature of TIP; (b) analysing its main expressions in sex, child, labour, and organ trafficking); (c) assessing their social impact; and evaluating the remedies available in various countertrafficking programs emerging in Southern African countries in recent years. Within this context it also examines the 4xP formula used in most trafficking studies to delineate and understand the subject. These refer to programs to address TIP in a preventative capacity, to protect its victims, to prosecute the perpetrators, and to develop Counter Trafficking Coalitions (CTC’s), or partnerships, between the state and civil society to address these heinous crimes as both law enforcement and public policy level. Particular attention is given to these issues in the light of the need to re-empower victims, ongoing globalisation, climate change and a post-COVID world which has increased the number of vulnerable persons while reducing the capacities of law enforcement systems.